Clinical evidence provided a rationale for considering Natural ASX as a therapeutic agent against inflammatory cytokine storm and associated risks in COVID-19 infection.
Early 2020, the World Health Organization (WHO) announced the outbreak of the coronavirus disease (COVID-19). The novel species of coronavirus SARS-CoV-2 has shown to elevate the levels of inflammatory factors such as interleukin-6 (IL-6) and Tumour Necrosis Factor-alpha (TNF-α) responsible for severe complications and infections in the lungs and leading to acute respiratory distress syndrome.
Studies have presented evidence showing Natural astaxanthin (ASX) – a naturally occurring and potent carotenoid often called “The King of Antioxidants” – to prevent against oxidative damage and reduce aggravation of the inflammatory responses.
The natural compound has shown powerful effect on the regulation and the reduction of cytokines and other inflammatory agents such as IL-6 and TNF-α. Evidence from more preclinical studies have supported its preventive actions against acute lung injury and acute respiratory distress syndrome.
Moreover, Natural ASX has a potent Peroxisome Proliferator Activated Receptors activity (PPARs). At cellular level, PPARs control a variety of target genes involved in lipid homeostasis, diabetes, cancer, cellular intermediary metabolism, and inflammation.
Natural ASX has a strong clinically proven safety profile, proven powerful antioxidant, potent anti-inflammatory, and immunomodulatory properties. These unique features position Natural ASX as an excellent choice against inflammation and its consequences. It is plausible why researchers have speculated that ASX could be considered as a potential adjunctive supplement.
Links to more relevant studies:
ASX protective barrier and its ability to improve the health in patients with COVID-19
Potential of natural ASX in alleviating the risk of cytokine storm in COVID-19
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